Sometimes pets ingest items or substances that cause serious harm if not treated immediately. If you suspect your pet has ingested or come in contact with something toxic, there are steps you can take to minimize the effects.
With accidental ingestion and toxicity cases, early treatment is key for a favorable prognosis. Pet owners are encouraged to call the ASPCA Animal Poison Control Center hotline at 888-426-4435 or the Pet Poison Hotline at 855-764-7661 (fees apply for these hotlines). These hotlines are a great resource for any animal poison-related emergency 24/7. Ask for your case number so it can be accessed at the hospital, if needed.
According to the ASPCA-APCC Hotline, the top pet toxin cases involve:
10. Gardening products (fertilizer, herbicides, fungicides)
9. Insecticides (insect and pest poisons)
8. Plants (indoor plants, outdoor plants, bouquets)
7. Rodentcides (mice and rat poisons)
6. Household items (paint, glue, cleaning supplies)
5. Veterinary products (such as pet medications)
4. Chocolate (baked goods, candy)
3. Food (such as xylitol, grapes/raisins, onions/garlic)
2. Human prescription medication
1. Over the counter medications (pain relievers, cold medicines, herbal supplements)
Over the past 10 years we have received many calls and questions about toxicities and accidental ingestions, but a few stand out:
Lily Toxicity (Cats)
Lilies in the true lily and daylily families are serious dangers to cats. The toxin, while still not fully understood, targets a cat’s kidneys and causes irreversible acute renal (kidney) failure. Toxins from lilies are rapidly absorbed after ingestion. Clinical signs can start in as little as five minutes and may include vomiting, anorexia, depression, and hypersalivation (excessive saliva production.) Renal failure starts within 12 to 24 hours post-ingestion. Later signs include polyuria (increased urination), depression, and anorexia. If a cat is not treated quickly, the prognosis is grave.
The most alarming part of lily toxicity is that all parts of a lily are toxic to a cat: leaves, petals, pollen, stems, even water in the vase has potential to cause harm. Common lilies toxic to cats include tiger lilies, stargazer lilies, day lilies, all Asiatic lilies, and Japanese show lilies. Easter lilies are also quite dangerous: many accidental ingestions happen around the Easter holiday.
While there is no “cure” for lily toxicity, treatments are available that greatly improve the prognosis if administered promptly. This may involve decontamination, such as inducing vomiting, gastric lavage, and administering activated charcoal with sorbitol. Additionally, cats are started on aggressive fluid therapy (2-3x maintenance) for 48-72 hours. Gastroprotectants are also helpful (antiemetics, antacid, phosphate binders.) Some cats that recover from acute toxicity may be prone to developing chronic kidney disease later in life.
If you are uncertain if a lily is toxic, keep it out of your cat’s reach until you can contact your veterinarian or contact a pet poison hotline for more details.

Asiatic Lily

Day Lily

Easter Lily

Tiger Lily
P
Toxicity (Cats)

Preventatives for fleas and ticks are important, but active ingredients are not dosed the same for dogs and cats.
- If left untreated, pyrethrin/pyrethroid toxicity can be fatal to cats.
Contact poison control or visit your veterinarian immediately if you suspect your pet has ingested or was exposed via the skin. Have the products you suspect your pet came in contact with available.
Xylitol Toxicity (Dogs)

Many sugar-free gums contain xylitol
Xylitol is an all-natural sweetener used as a sugar substitute. Xylitol’s appeal comes from its similarities to sugar with less calories and lower glycemic index. Xylitol also contains anti-cavity properties. Although xylitol is considered a safe sugar substitute in humans, it is toxic to dogs. Just a few pieces of sugar-free gum have the ability to affect dogs within minutes. There is no antidote for xylitol toxicity, but the prognosis is good for dogs who are treated quickly.
Human and canine blood sugar levels are both controlled by the pancreas and its ability to release insulin. Xylitol does not affect the release of insulin in humans, but triggers canines to release a large dose of insulin. This causes a spike in blood sugar and can result in hypoglycemia (a dangerous drop in blood sugar.)
Common products containing xylitol are chewing gums, candies, mints, toothpastes, and mouthwashes. Some baking mixes, puddings, baked goods, nut butters, and home and beauty products may also contain xylitol, so pet owners are encouraged to read product labels.
As little as 50mg of xylitol per pound of body weight can cause hypoglycemia and its effects can begin to occur in as little as 10 minutes. While different brands contain different amounts, typically the range is 300 to 1500 mg per piece. To put this into perspective, if a piece of gum containing xylitol contains 1,000 mg, a 20 lb. dog may experience toxicity after ingesting just one piece.
Clinical signs develop rapidly, usually within the first 15-30 minutes after ingestion. Signs include vomiting, ataxia (lack of coordination,) lethargy, tremors, seizures, vomiting, and coma. Untreated cases can develop liver failure in the days following the ingestion. The sooner a dog presenting with these symptoms is seen by a veterinary professional, the better the prognosis will be.
Drug-Related Toxicities

Marijuana
The nation is decriminalizing and adopting new policies on drugs which puts more pets at risk of a drug-related toxicity. Regardless of the drug, a pet’s prognosis is greatly improved the sooner proper treatment begins.
The most common type of drug-related toxicity seen at VREC marijuana. Pets can be exposed via smoke inhalation, ingestion of the marijuana itself, or through ingestion of foods with marijuana in them (especially baked goods.) Clinical signs of marijuana exposure can include dilated pupils, agitation or sedation, tremors, a “drunken” walk, general disorientation, vomiting, drooling, and urinary incontinence. Both dogs and cats are susceptible of these signs, which may develop as soon as five minutes to 12 hours after exposure.
If you suspect your pet has ingested an illicit drug, please do not hesitate to bring them in for evaluation. Some may have an aversion to seek care due to stigma or the fear of legal repercussions. Veterinarians provide care regardless of the situation and will not call the police!
In suspected cases of drug exposure, veterinary staff greatly prefer honesty as it helps quickly diagnose and treat a pet. Key information such as type of substance, time of exposure, time of first noticed clinical signs, along with their type and duration, are incredibly helpful. Veterinarians care little about the illegal aspects of drugs – their goal is to treat pets to the best of their abilities.
Chocolate
One of the most commonly searched toxicities, chocolate contains both theobromine and caffeine, both of which speed the heart rate and stimulate the nervous system. Structurally similar, these two chemicals belong to a group of chemicals called methylxanthines. In human medicine they can be used as diuretics, heart stimulants, and blood vessel dilators. Pets are not built the same as humans and cannot easily metabolize these substances.
While cats are also at risk of chocolate toxicity, the overwhelming majority of cases treated are dogs. The amount of caffeine and theobromide in chocolate varies wildly on the type of chocolate. Cocoa beans and powder are the most concerning, followed by baker’s chocolate, semisweet dark chocolate, and milk chocolate. “White” chocolate has an insignificant amount of methylxanthines to cause major problems, but should still not be given to pets. It should also be noted that some companies sell cocoa bean mulch, which is still cocoa beans — and quite toxic to pets if ingested!
A pet’s risk of becoming sick from chocolate depends on several factors: the type of chocolate consumed, the quantity ingested, and the weight of the dog. A few squares of dark chocolate may not be life threatening to a Great Dane but may cause a Pug serious concern.
Clinical signs of chocolate poisoning may develop over the course of a few hours post ingestion and may include:
- Vomiting
- Diarrhea
- Restlessness
- Rapid and/or irregular heartbeat
- Excessive thirst and/or urination
- Muscle tremors
- Seizures
- Heart problems
If a pet is suspected of consuming chocolate, contact a pet poison control immediately. Include details like the type of chocolate consumed, elapsed time since ingestion, any clinical signs you may notice, and the pet’s weight. Treatment may include intravenous fluid therapy, medication to induce vomiting, or activated charcoal to block absorption.
Snake bites
Although not a “poison,” VREC receives calls about snake bites (especially in warmer months.) Pennsylvania is home to over 20 different snake species. Three species are venomous: Eastern Copperhead, Timber Rattlesnake, and Eastern Massasauga. All venomous snakes found in Pennsylvania possess key indicators: vertical eye pupils (similar to a cat’s eyes), an indentation on each side of the head between the eye and nostril, and a single row of scales on the underside of the tail.
Pennsylvania’s venomous snakes are generally nonagressive but will not hesitate to fight back if threatened. Snake bites usually occur while a pet (or person) is attempting to advance on or handle a snake. If a pet is bitten, remain calm and contact a veterinarian for further instruction. Keep your pet as immobile as possible until seen by a medical professional. If you believe your pet has been bitten by a venomous snake, contact VREC immediately. We stock antivenin, an anti-venom product which counteracts the dangerous effects of snake venom. In order to work, antivenin needs to be administered within a few hours after the bite.